Q: Dexmedetomidine (Precedex) should be use in caution with?

A) Renal failure

B) Liver Failure

C) Adrenal crisis

D) Tachycardia

E) Coagulopathy



Answer: ( B) Liver failure

Dexmedetomidine's undergoes hepatic metabolism. Caution should be used in patients with severe hepatic failure as elimination half life may be more than doubled. Normally dexmedetomidine has an elimination half life of 2 hours.

It has no effect in renal failure or adrenal crisis. It does not effect coagulation. Dexmedetomidine causes bradycardia and should be use with caution in bradycardia.